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| Sandrine Holt | Terri Morales | |
| Mike Epps | L.J. | |
| Razaaq Adoti | Peyton Wells | |
| Jared Harris | Dr. Ashford | |
| Thomas Kretschmann | Major Cain | |
| Dave Nichols | Cpt. Henderson | |
| Milla Jovovich | Alice | |
| Zack Ward | Nicholai Ginovaeff | |
| Sophie Vavasseur | Angie Ashford | |
| Sienna Guillory | Jill Valentine | |
| Oded Fehr | Carlos Olivera | |
| Matthew G. Taylor | Nemesis | |
| Geoffrey Pounsett | MacKenzie | |
| Ian Glen | Dr. Isaacs | |
| Stefen Hayes | Yuri Loginova | 
| Director | 
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| Producer | Paul W.S. Anderson Paul Anderson | ||
| Writer | Paul W.S. Anderson | ||
| Cinematography | Christian Sebaldt | ||
| Musician | Jeff Danna | 
|  | Something evil's lurking in Raccoon City, and the fearless Alice is one of only a few willing to put her life on the line to investigate the malevolent force. A virus is attacking the area's denizens, turning them into the undead. With the help of her colleague, Jill, Alice sets out to uncover the truth, even as she fends off an experimental weapon, code name Nemesis. | 
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