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| Danny Glover | Lieutenant Mike Harrigan | |
| Gary Busey | Peter Keyes | |
| Kevin Peter Hall | The Predator | |
| Adam Baldwin | Garber | |
| Robert Davi | Captain Phil Heinemann | |
| Kent McCord | Captain B. Pilgrim | |
| Bill Paxton | Jerry Lambert | |
| Calvin Lockhart | King Willie | |
| Rubén Blades | Danny Archuleta | |
| Steve Kahan | Sergeant | |
| Maria Conchita Alonso | Leona | |
| Morton Downey Jr. | Tony Pope | |
| Henry Kingi | El Scorpio | |
| Corey Rand | Ramon Vega | |
| Elpidia Carrillo | Anna | 
| Director | 
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| Producer | John Davis Joel Silver | ||
| Writer | Jim Thomas John Thomas | ||
| Cinematography | Peter Levy | ||
| Musician | Alan Silvestri | 
|  | Ten years after a band of mercenaries first battled a vicious alien, the invisible creature from another world has returned to Earth -- and this time, it's drawn to the gang-ruled and ravaged city of Los Angeles. When it starts murdering drug dealers, detective-lieutenant Mike Harrigan and his police force set out to capture the creature, ignoring warnings from a mysterious government agent to stay away. | 
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