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| Uma Thurman | Irene Cassini | |
| Ethan Hawke | Vincent Freeman | |
| Alan Arkin | Det. Hugo | |
| Carlton Bembry | Gattaca Hoover | |
| Jayne Brook | Marie | |
| Una Damon | Head Nurse | |
| Xander Berkeley | Lamar | |
| Elizabeth Dennehy | Pre-School Teacher | |
| Mason Gamble | Younger Vincent | |
| Elias Koteas | Antonio | |
| Vincent Nielson | Younger Anton | |
| Maya Rudolph | Delivery Nurse | |
| Blair Underwood | Geneticist | |
| Gore Vidal | Director Josef | |
| Ernest Borgnine | Caesar | 
| Director | 
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| Producer | Michael Shamberg Danny DeVito | ||
| Writer | Andrew Niccol | ||
| Cinematography | Slawomir Idziak | ||
| Musician | Michael Nyman | 
|  | Science fiction drama about a future society in the era of indefinite eugenics where humans are set on a life course depending on their DNA. The young Vincent Freeman is born with a condition that would prevent him from space travel, yet he is determined to infiltrate the GATTACA space program. | 
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